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Genome-wide Screen for Culture Adaptation and Tumorigenicity-Related Genes in Human Pluripotent Stem Cells
Human pluripotent stem cells (hPSCs) acquire genetic changes during their propagation in culture that can affect their use in research and future therapies. To identify the key genes involved in selective advantage during culture adaptation and tumorigenicity of hPSCs, we generated a genome-wide scr...
Autores principales: | Weissbein, Uri, Peretz, Mordecai, Plotnik, Omer, Yanuka, Ofra, Sagi, Ido, Golan-Lev, Tamar, Benvenisty, Nissim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348297/ https://www.ncbi.nlm.nih.gov/pubmed/30660107 http://dx.doi.org/10.1016/j.isci.2018.12.031 |
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