A CRISPR Screen Identifies LAPTM4A and TM9SF Proteins as Glycolipid-Regulating Factors

Glycosphingolipids (GSLs) are produced by various GSL-synthesizing enzymes, but post-translational regulation of these enzymes is incompletely understood. To address this knowledge disparity, we focused on biosynthesis of globotriaosylceramide (Gb3), the Shiga toxin (STx) receptor, and performed a g...

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Detalles Bibliográficos
Autores principales: Yamaji, Toshiyuki, Sekizuka, Tsuyoshi, Tachida, Yuriko, Sakuma, Chisato, Morimoto, Kanta, Kuroda, Makoto, Hanada, Kentaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348303/
https://www.ncbi.nlm.nih.gov/pubmed/30660999
http://dx.doi.org/10.1016/j.isci.2018.12.039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348303/
https://www.ncbi.nlm.nih.gov/pubmed/30660999
http://dx.doi.org/10.1016/j.isci.2018.12.039

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