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Gene Expression and Methylation Analysis in Melanomas and Melanocytes From the Same Patient: Loss of NPM2 Expression Is a Potential Immunohistochemical Marker for Melanoma

DNA methylation is considered the primary epigenetic mechanism underlying the development of malignant melanoma. Since DNA methylation can be influenced by environmental factors, it is preferable to compare cancer and normal cells from the same patient. In order to compare the methylation status in...

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Detalles Bibliográficos
Autores principales: Fujiwara, Susumu, Nagai, Hiroshi, Jimbo, Haruki, Jimbo, Naoe, Tanaka, Tomoyo, Inoie, Masukazu, Nishigori, Chikako
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348333/
https://www.ncbi.nlm.nih.gov/pubmed/30719424
http://dx.doi.org/10.3389/fonc.2018.00675