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Renin-angiotensin system inhibitor attenuates oxidative stress induced human coronary artery endothelial cell dysfunction via the PI3K/AKT/mTOR pathway

INTRODUCTION: The renin-angiotensin system is associated with blood pressure regulation, inflammation, oxidative stress and insulin resistance. It can decrease intracellular oxidative stress. Stimulation with H(2)O(2) leads to increased oxidative stress and activation of the AKT/mTOR pathway. Howeve...

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Detalles Bibliográficos
Autores principales: Shi, Xuekun, Guan, Yuhua, Jiang, Shaoyan, Li, Tiandong, Sun, Bing, Cheng, Huan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348342/
https://www.ncbi.nlm.nih.gov/pubmed/30697266
http://dx.doi.org/10.5114/aoms.2018.74026