Trichostatin A activates FOXO1 and induces autophagy in osteosarcoma

INTRODUCTION: Histone deacetylase inhibitors (HDACIs) inhibit human osteosarcoma growth and cause apoptosis. Previously, we reported that HDACIs induce autophagy via the FOXO1 pathway. Whether there is involvement of autophagy in anti-osteosarcoma activity of HDACIs is still unknown. MATERIAL AND ME...

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Detalles Bibliográficos
Autores principales: Bai, Yunjuan, Chen, Yun, Chen, Xiaochen, Jiang, Jiukun, Wang, Xiao, Wang, Liping, Wang, Jigang, Zhang, Jianbin, Gao, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2018
Materias:
Basic Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348367/
https://www.ncbi.nlm.nih.gov/pubmed/30697272
http://dx.doi.org/10.5114/aoms.2018.73860

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348367/
https://www.ncbi.nlm.nih.gov/pubmed/30697272
http://dx.doi.org/10.5114/aoms.2018.73860

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