5‐Oxyacetic Acid Modification Destabilizes Double Helical Stem Structures and Favors Anionic Watson–Crick like cmo(5)U‐G Base Pairs

Watson–Crick like G‐U mismatches with tautomeric G(enol) or U(enol) bases can evade fidelity checkpoints and thereby contribute to translational errors. The 5‐oxyacetic acid uridine (cmo(5)U) modification is a base modification at the wobble position on tRNAs and is presumed to expand the decoding c...

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Detalles Bibliográficos
Autores principales: Strebitzer, Elisabeth, Rangadurai, Atul, Plangger, Raphael, Kremser, Johannes, Juen, Michael Andreas, Tollinger, Martin, Al‐Hashimi, Hashim M., Kreutz, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348377/
https://www.ncbi.nlm.nih.gov/pubmed/30300940
http://dx.doi.org/10.1002/chem.201805077

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348377/
https://www.ncbi.nlm.nih.gov/pubmed/30300940
http://dx.doi.org/10.1002/chem.201805077

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