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Chemoselective α,β‐Dehydrogenation of Saturated Amides

We report a method for the selective α,β‐dehydrogenation of amides in the presence of other carbonyl moieties under mild conditions. Our strategy relies on electrophilic activation coupled to in situ selective selenium‐mediated dehydrogenation. The α,β‐unsaturated products were obtained in moderate...

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Detalles Bibliográficos
Autores principales: Teskey, Christopher J., Adler, Pauline, Gonçalves, Carlos R., Maulide, Nuno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348382/
https://www.ncbi.nlm.nih.gov/pubmed/30332524
http://dx.doi.org/10.1002/anie.201808794