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Rapid Mapping of Protein Interactions Using Tag‐Transfer Photocrosslinkers

Analysing protein complexes by chemical crosslinking‐mass spectrometry (XL‐MS) is limited by the side‐chain reactivities and sizes of available crosslinkers, their slow reaction rates, and difficulties in crosslink enrichment, especially for rare, transient or dynamic complexes. Here we describe two...

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Detalles Bibliográficos
Autores principales: Horne, Jim E., Walko, Martin, Calabrese, Antonio N., Levenstein, Mark A., Brockwell, David J., Kapur, Nikil, Wilson, Andrew J., Radford, Sheena E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348423/
https://www.ncbi.nlm.nih.gov/pubmed/30393918
http://dx.doi.org/10.1002/anie.201809149