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Rapid Mapping of Protein Interactions Using Tag‐Transfer Photocrosslinkers
Analysing protein complexes by chemical crosslinking‐mass spectrometry (XL‐MS) is limited by the side‐chain reactivities and sizes of available crosslinkers, their slow reaction rates, and difficulties in crosslink enrichment, especially for rare, transient or dynamic complexes. Here we describe two...
Autores principales: | Horne, Jim E., Walko, Martin, Calabrese, Antonio N., Levenstein, Mark A., Brockwell, David J., Kapur, Nikil, Wilson, Andrew J., Radford, Sheena E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348423/ https://www.ncbi.nlm.nih.gov/pubmed/30393918 http://dx.doi.org/10.1002/anie.201809149 |
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