Potent Metabolic Sialylation Inhibitors Based on C-5-Modified Fluorinated Sialic Acids

[Image: see text] Sialic acid sugars on mammalian cells regulate numerous biological processes, while aberrant expression of sialic acid is associated with diseases such as cancer and pathogenic infection. Inhibition of the sialic acid biosynthesis may therefore hold considerable therapeutic potenti...

Descripción completa

Detalles Bibliográficos
Autores principales: Heise, Torben, Pijnenborg, Johan F. A., Büll, Christian, van Hilten, Niek, Kers-Rebel, Esther D., Balneger, Natasja, Elferink, Hidde, Adema, Gosse J., Boltje, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348442/
https://www.ncbi.nlm.nih.gov/pubmed/30543426
http://dx.doi.org/10.1021/acs.jmedchem.8b01757

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348442/
https://www.ncbi.nlm.nih.gov/pubmed/30543426
http://dx.doi.org/10.1021/acs.jmedchem.8b01757

Ejemplares similares