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Potent Metabolic Sialylation Inhibitors Based on C-5-Modified Fluorinated Sialic Acids
[Image: see text] Sialic acid sugars on mammalian cells regulate numerous biological processes, while aberrant expression of sialic acid is associated with diseases such as cancer and pathogenic infection. Inhibition of the sialic acid biosynthesis may therefore hold considerable therapeutic potenti...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348442/ https://www.ncbi.nlm.nih.gov/pubmed/30543426 http://dx.doi.org/10.1021/acs.jmedchem.8b01757 |