Droplet digital PCR as an alternative to FISH for MYCN amplification detection in human neuroblastoma FFPE samples

BACKGROUND: MYCN amplification directly correlates with the clinical course of neuroblastoma and poor patient survival, and serves as the most critical negative prognostic marker. Although fluorescence in situ hybridization (FISH) remains the gold standard for clinical diagnosis of MYCN status in ne...

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Detalles Bibliográficos
Autores principales: Somasundaram, Dinesh Babu, Aravindan, Sheeja, Yu, Zhongxin, Jayaraman, Muralidharan, Tran, Ngoc T. B., Li, Shibo, Herman, Terence S., Aravindan, Natarajan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348625/
https://www.ncbi.nlm.nih.gov/pubmed/30691436
http://dx.doi.org/10.1186/s12885-019-5306-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348625/
https://www.ncbi.nlm.nih.gov/pubmed/30691436
http://dx.doi.org/10.1186/s12885-019-5306-0

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