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Rational construction of genome-reduced and high-efficient industrial Streptomyces chassis based on multiple comparative genomic approaches
BACKGROUND: Streptomyces chattanoogensis L10 is the industrial producer of natamycin and has been proved a highly efficient host for diverse natural products. It has an enormous potential to be developed as a versatile cell factory for production of heterologous secondary metabolites. Here we develo...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348691/ https://www.ncbi.nlm.nih.gov/pubmed/30691531 http://dx.doi.org/10.1186/s12934-019-1055-7 |