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Long-term interleukin-33 treatment delays disease onset and alleviates astrocytic activation in a transgenic mouse model of amyotrophic lateral sclerosis

Inflammation is a prominent feature of the neuropathology of amyotrophic lateral sclerosis (ALS). Emerging evidence suggests that inflammatory cascades contributing to the disease progression are not restricted to the central nervous system (CNS) but also occur peripherally. Indeed, alterations in T...

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Detalles Bibliográficos
Autores principales: Korhonen, Paula, Pollari, Eveliina, Kanninen, Katja M., Savchenko, Ekaterina, Lehtonen, Šárka, Wojciechowski, Sara, Pomeshchik, Yuriy, Van Den Bosch, Ludo, Goldsteins, Gundars, Koistinaho, Jari, Malm, Tarja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348738/
https://www.ncbi.nlm.nih.gov/pubmed/30705990
http://dx.doi.org/10.1016/j.ibror.2019.01.005