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Long-term interleukin-33 treatment delays disease onset and alleviates astrocytic activation in a transgenic mouse model of amyotrophic lateral sclerosis
Inflammation is a prominent feature of the neuropathology of amyotrophic lateral sclerosis (ALS). Emerging evidence suggests that inflammatory cascades contributing to the disease progression are not restricted to the central nervous system (CNS) but also occur peripherally. Indeed, alterations in T...
Autores principales: | Korhonen, Paula, Pollari, Eveliina, Kanninen, Katja M., Savchenko, Ekaterina, Lehtonen, Šárka, Wojciechowski, Sara, Pomeshchik, Yuriy, Van Den Bosch, Ludo, Goldsteins, Gundars, Koistinaho, Jari, Malm, Tarja |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348738/ https://www.ncbi.nlm.nih.gov/pubmed/30705990 http://dx.doi.org/10.1016/j.ibror.2019.01.005 |
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