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In Vivo Biokinetics of (177)Lu-OPS201 in Mice and Pigs as a Model for Predicting Human Dosimetry

INTRODUCTION: (177)Lu-OPS201 is a high-affinity somatostatin receptor subtype 2 antagonist for PRRT in patients with neuroendocrine tumors. The aim is to find the optimal scaling for dosimetry and to compare the biokinetics of (177)Lu-OPS201 in animals and humans. METHODS: Data on biokinetics of (17...

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Detalles Bibliográficos
Autores principales: Beykan, Seval, Fani, Melpomeni, Jensen, Svend Borup, Nicolas, Guillaume, Wild, Damian, Kaufmann, Jens, Lassmann, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348830/
https://www.ncbi.nlm.nih.gov/pubmed/30733648
http://dx.doi.org/10.1155/2019/6438196