Detection of Active Caspase-3 in Mouse Models of Stroke and Alzheimer's Disease with a Novel Dual Positron Emission Tomography/Fluorescent Tracer [(68)Ga]Ga-TC3-OGDOTA

Apoptosis is a feature of stroke and Alzheimer's disease (AD), yet there is no accepted method to detect or follow apoptosis in the brain in vivo. We developed a bifunctional tracer [(68)Ga]Ga-TC3-OGDOTA containing a cell-penetrating peptide separated from fluorescent Oregon Green and (68)Ga-bo...

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Detalles Bibliográficos
Autores principales: Ostapchenko, Valeriy G., Snir, Jonatan, Suchy, Mojmir, Fan, Jue, Cobb, M. Rebecca, Chronik, Blaine A., Kovacs, Michael, Prado, Vania F., Hudson, Robert H. E., Pasternak, Stephen H., Prado, Marco A. M., Bartha, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348924/
https://www.ncbi.nlm.nih.gov/pubmed/30755766
http://dx.doi.org/10.1155/2019/6403274

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348924/
https://www.ncbi.nlm.nih.gov/pubmed/30755766
http://dx.doi.org/10.1155/2019/6403274

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