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miRNA length variation during macrophage stimulation confounds the interpretation of results: implications for miRNA quantification by RT-qPCR

Most microRNAs (miRNAs) are expressed as a mix of length isoforms (referred to as isomiRs). IsomiR stoichiometry can be differentially impacted upon cell stimulation, as recently evidenced by our group in the context of immune responses induced by type-I interferon (IFN). Here, we revisit published...

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Detalles Bibliográficos
Autores principales: Pillman, Katherine A., Goodall, Gregory J., Bracken, Cameron P., Gantier, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348984/
https://www.ncbi.nlm.nih.gov/pubmed/30487268
http://dx.doi.org/10.1261/rna.069047.118