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RBP-Maps enables robust generation of splicing regulatory maps

Alternative splicing of pre-messenger RNA transcripts enables the generation of multiple protein isoforms from the same gene locus, providing a major source of protein diversity in mammalian genomes. RNA binding proteins (RBPs) bind to RNA to control splice site choice and define which exons are inc...

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Detalles Bibliográficos
Autores principales: Yee, Brian A., Pratt, Gabriel A., Graveley, Brenton R., Van Nostrand, Eric L., Yeo, Gene W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348990/
https://www.ncbi.nlm.nih.gov/pubmed/30413564
http://dx.doi.org/10.1261/rna.069237.118