Monitoring metal–amyloid-β complexation by a FRET-based probe: design, detection, and inhibitor screening

Aggregation of amyloidogenic peptides could cause the onset and progression of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. These amyloidogenic peptides can coordinate to metal ions, including Zn(ii), which can subsequently affect the peptides' aggr...

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Detalles Bibliográficos
Autores principales: Lee, Hyuck Jin, Lee, Young Geun, Kang, Juhye, Yang, Seung Hyun, Kim, Ju Hwan, Ghisaidoobe, Amar B. T., Kang, Hyo Jin, Lee, Sang-Rae, Lim, Mi Hee, Chung, Sang J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349019/
https://www.ncbi.nlm.nih.gov/pubmed/30774894
http://dx.doi.org/10.1039/c8sc04943b

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349019/
https://www.ncbi.nlm.nih.gov/pubmed/30774894
http://dx.doi.org/10.1039/c8sc04943b

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