Suppression of miR-21-3p enhances TRAIL-mediated apoptosis in liver cancer stem cells by suppressing the PI3K/Akt/Bad cascade via regulating PTEN

BACKGROUND: TNF-related apoptosis-inducing ligand (TRAIL) functions as a selective apoptosis-inducing ligand in cancer cells with normal cells remaining unaffected; however, resistance limits its anticancer properties. Cancer stem cells (CSCs) are involved in the treatment of resistant cancer cases...

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Detalles Bibliográficos
Autores principales: Zhu, Yingwei, Tang, Hong, Zhang, Lili, Gong, Lei, Wu, Gaojue, Ni, Jingbin, Tang, Xuejun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349085/
https://www.ncbi.nlm.nih.gov/pubmed/30774424
http://dx.doi.org/10.2147/CMAR.S183328

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349085/
https://www.ncbi.nlm.nih.gov/pubmed/30774424
http://dx.doi.org/10.2147/CMAR.S183328

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