A structurally heterogeneous transition state underlies coupled binding and folding of disordered proteins

Many intrinsically disordered proteins (IDPs) attain a well-defined structure in a coupled folding and binding reaction with another protein. Such reactions may involve early to late formation of different native structural regions along the reaction pathway. To obtain insights into the transition s...

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Detalles Bibliográficos
Autores principales: Karlsson, Elin, Andersson, Eva, Dogan, Jakob, Gianni, Stefano, Jemth, Per, Camilloni, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2019
Materias:
Protein Structure and Folding
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349112/
https://www.ncbi.nlm.nih.gov/pubmed/30514761
http://dx.doi.org/10.1074/jbc.RA118.005854

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349112/
https://www.ncbi.nlm.nih.gov/pubmed/30514761
http://dx.doi.org/10.1074/jbc.RA118.005854

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