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Autocrine VEGF signalling on M2 macrophages regulates PD‐L1 expression for immunomodulation of T cells

M2‐polarized macrophages, on one hand, can promote tumour vascularization by producing proangiogenic factors, such as vascular endothelial growth factor (VEGF). On the other hand, the expression of VEGF receptors (VEGFR) in this cell lineage was also reported. Although the function of VEGF/VEGFR axi...

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Detalles Bibliográficos
Autores principales: Lai, Yin‐Siew, Wahyuningtyas, Rika, Aui, Shin‐Peir, Chang, Ko‐Tung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349155/
https://www.ncbi.nlm.nih.gov/pubmed/30456891
http://dx.doi.org/10.1111/jcmm.14027