Leonurine suppresses neuroinflammation through promoting oligodendrocyte maturation

Focal inflammation and remyelination failure are major hallmarks of multiple sclerosis and its animal model, experimental autoimmune encephalomyelitis (EAE). In this study, we found that leonurine, a bioactive alkaloid, alleviated EAE disease severity along with reduced central nervous system inflam...

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Detalles Bibliográficos
Autores principales: Jin, Min, Li, Qian, Gu, Yuting, Wan, Bing, Huang, Jiefang, Xu, Xuanbai, Huang, Rui, Zhang, Yanyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349161/
https://www.ncbi.nlm.nih.gov/pubmed/30556290
http://dx.doi.org/10.1111/jcmm.14053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349161/
https://www.ncbi.nlm.nih.gov/pubmed/30556290
http://dx.doi.org/10.1111/jcmm.14053

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