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Leonurine suppresses neuroinflammation through promoting oligodendrocyte maturation
Focal inflammation and remyelination failure are major hallmarks of multiple sclerosis and its animal model, experimental autoimmune encephalomyelitis (EAE). In this study, we found that leonurine, a bioactive alkaloid, alleviated EAE disease severity along with reduced central nervous system inflam...
Autores principales: | Jin, Min, Li, Qian, Gu, Yuting, Wan, Bing, Huang, Jiefang, Xu, Xuanbai, Huang, Rui, Zhang, Yanyun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349161/ https://www.ncbi.nlm.nih.gov/pubmed/30556290 http://dx.doi.org/10.1111/jcmm.14053 |
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