Inhibiting the urokinase‐type plasminogen activator receptor system recovers STZ‐induced diabetic nephropathy

The urokinase‐type plasminogen activator (uPA) receptor (uPAR) participates to the mechanisms causing renal damage in response to hyperglycaemia. The main function of uPAR in podocytes (as well as soluble uPAR ‐(s)uPAR‐ from circulation) is to regulate podocyte function through αvβ3 integrin/Rac‐1....

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Detalles Bibliográficos
Autores principales: Dal Monte, Massimo, Cammalleri, Maurizio, Pecci, Valeria, Carmosino, Monica, Procino, Giuseppe, Pini, Alessandro, De Rosa, Mario, Pavone, Vincenzo, Svelto, Maria, Bagnoli, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349167/
https://www.ncbi.nlm.nih.gov/pubmed/30426662
http://dx.doi.org/10.1111/jcmm.14004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349167/
https://www.ncbi.nlm.nih.gov/pubmed/30426662
http://dx.doi.org/10.1111/jcmm.14004

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