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O‐GlcNAcylation promotes colorectal cancer progression by regulating protein stability and potential catcinogenic function of DDX5

The RNA helicase p68 (DDX5), a key player in RNA metabolism, belongs to the DEAD box family and is involved in the development of colorectal cancer. Here, we found both DDX5 and O‐GlcNAcylation are up‐regulated in colorectal cancer. In addition, DDX5 protein level is significantly positively correla...

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Detalles Bibliográficos
Autores principales: Wu, Nan, Jiang, Mingzuo, Han, Yuying, Liu, Haiming, Chu, Yi, Liu, Hao, Cao, Jiayi, Hou, Qiuqiu, Zhao, Yu, Xu, Bing, Xie, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349181/
https://www.ncbi.nlm.nih.gov/pubmed/30484950
http://dx.doi.org/10.1111/jcmm.14038