Two human MARs effectively increase transgene expression in transfected CHO cells

Matrix attachment regions (MARs) can enhance the expression level of transgene in Chinese hamster ovaries (CHO) cell expression system. However, improvements in function and analyses of the mechanism remains unclear. In this study, we screened two new and more functional MAR elements from the human...

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Detalles Bibliográficos
Autores principales: Li, Qin, Zhao, Chun‐peng, Lin, Yan, Song, Chao, Wang, Fang, Wang, Tian‐yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Short Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349195/
https://www.ncbi.nlm.nih.gov/pubmed/30450759
http://dx.doi.org/10.1111/jcmm.14018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349195/
https://www.ncbi.nlm.nih.gov/pubmed/30450759
http://dx.doi.org/10.1111/jcmm.14018

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