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Two human MARs effectively increase transgene expression in transfected CHO cells
Matrix attachment regions (MARs) can enhance the expression level of transgene in Chinese hamster ovaries (CHO) cell expression system. However, improvements in function and analyses of the mechanism remains unclear. In this study, we screened two new and more functional MAR elements from the human...
Autores principales: | Li, Qin, Zhao, Chun‐peng, Lin, Yan, Song, Chao, Wang, Fang, Wang, Tian‐yun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349195/ https://www.ncbi.nlm.nih.gov/pubmed/30450759 http://dx.doi.org/10.1111/jcmm.14018 |
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