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Why SNP rs227584 is associated with human BMD and fracture risk? A molecular and cellular study in bone cells

A large number of SNPs significant for osteoporosis (OP) had been identified by genome‐wide association studies. However, the underlying association mechanisms were largely unknown. From the perspective of protein phosphorylation, gene expression regulation, and bone cell activity, this study aims t...

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Detalles Bibliográficos
Autores principales: Zhou, Xu, Qiu, Ying‐Hua, He, Pei, Jiang, Fei, Wu, Long‐Fei, Lu, Xin, Lei, Shu‐Feng, Deng, Fei‐Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349212/
https://www.ncbi.nlm.nih.gov/pubmed/30370607
http://dx.doi.org/10.1111/jcmm.13991