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Targeting PRMT5/Akt signalling axis prevents human lung cancer cell growth

The emerging evidence reveals that protein arginine methyltransferase 5 (PRMT5) is involved in regulation of tumour cell proliferation and cancer development. Nevertheless, the exact role of PRMT5 in human lung cancer cell proliferation and the underlying molecular mechanism remains largely obscure....

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Detalles Bibliográficos
Autores principales: Zhang, Shikui, Ma, Yaqiong, Hu, Xiaoyan, Zheng, Yonghua, Chen, Xiaoke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349228/
https://www.ncbi.nlm.nih.gov/pubmed/30461193
http://dx.doi.org/10.1111/jcmm.14036