Conditioned medium from amniotic cells protects striatal degeneration and ameliorates motor deficits in the R6/2 mouse model of Huntington's disease

Inflammation significantly impacts the progression of Huntington's disease (HD) and the mutant HTT protein determines a pro‐inflammatory activation of microglia. Mesenchymal stem/stromal cells (MSC) from the amniotic membrane (hAMSC), and their conditioned medium (CM‐hAMSC), have been shown to...

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Detalles Bibliográficos
Autores principales: Giampà, Carmela, Alvino, Alessandra, Magatti, Marta, Silini, Antonietta R., Cardinale, Antonella, Paldino, Emanuela, Fusco, Francesca R., Parolini, Ornella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349233/
https://www.ncbi.nlm.nih.gov/pubmed/30585395
http://dx.doi.org/10.1111/jcmm.14113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349233/
https://www.ncbi.nlm.nih.gov/pubmed/30585395
http://dx.doi.org/10.1111/jcmm.14113

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