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Conditioned medium from amniotic cells protects striatal degeneration and ameliorates motor deficits in the R6/2 mouse model of Huntington's disease
Inflammation significantly impacts the progression of Huntington's disease (HD) and the mutant HTT protein determines a pro‐inflammatory activation of microglia. Mesenchymal stem/stromal cells (MSC) from the amniotic membrane (hAMSC), and their conditioned medium (CM‐hAMSC), have been shown to...
Autores principales: | Giampà, Carmela, Alvino, Alessandra, Magatti, Marta, Silini, Antonietta R., Cardinale, Antonella, Paldino, Emanuela, Fusco, Francesca R., Parolini, Ornella |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349233/ https://www.ncbi.nlm.nih.gov/pubmed/30585395 http://dx.doi.org/10.1111/jcmm.14113 |
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