Pancreatic fibroblast growth factor 21 protects against type 2 diabetes in mice by promoting insulin expression and secretion in a PI3K/Akt signaling‐dependent manner

Fibroblast growth factor 21 (FGF21) is important in glucose, lipid homeostasis and insulin sensitivity. However, it remains unknown whether FGF21 is involved in insulin expression and secretion that are dysregulated in type 2 diabetes mellitus (T2DM). In this study, we found that FGF21 was down‐regu...

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Detalles Bibliográficos
Autores principales: Pan, Yingying, Wang, Baile, Zheng, Jujia, Xiong, Rongrong, Fan, Zhichao, Ye, Yanna, Zhang, Saisai, Li, Qinyao, Gong, Fanghua, Wu, Chaoming, Lin, Zhuofeng, Li, Xiaokun, Pan, Xuebo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349243/
https://www.ncbi.nlm.nih.gov/pubmed/30461198
http://dx.doi.org/10.1111/jcmm.14007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349243/
https://www.ncbi.nlm.nih.gov/pubmed/30461198
http://dx.doi.org/10.1111/jcmm.14007

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