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Lapachol and synthetic derivatives: in vitro and in vivo activities against Bothrops snake venoms
BACKGROUND: It is known that local tissue injuries incurred by snakebites are quickly instilled causing extensive, irreversible, tissue destruction that may include loss of limb function or even amputation. Such injuries are not completely neutralized by the available antivenins, which in general ar...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349327/ https://www.ncbi.nlm.nih.gov/pubmed/30689661 http://dx.doi.org/10.1371/journal.pone.0211229 |