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Small molecule nAS‐E targeting cAMP response element binding protein (CREB) and CREB‐binding protein interaction inhibits breast cancer bone metastasis

Bone is the most common metastatic site for breast cancer. The excessive osteoclast activity in the metastatic bone lesions often produces osteolysis. The cyclic‐AMP (cAMP)‐response element binding protein (CREB) serves a variety of biological functions including the transformation and immortalizati...

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Detalles Bibliográficos
Autores principales: Jiang, Min, Yan, Yufei, Yang, Kai, Liu, Zhuochao, Qi, Jin, Zhou, Hanbing, Qian, Niandong, Zhou, Qi, Wang, Tianqi, Xu, Xing, Xiao, Xiangshu, Deng, Lianfu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349349/
https://www.ncbi.nlm.nih.gov/pubmed/30461194
http://dx.doi.org/10.1111/jcmm.14024