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Computational and experimental analysis of bioactive peptide linear motifs in the integrin adhesome

Therapeutic modulation of protein interactions is challenging, but short linear motifs (SLiMs) represent potential targets. Focal adhesions play a central role in adhesion by linking cells to the extracellular matrix. Integrins are central to this process, and many other intracellular proteins are c...

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Detalles Bibliográficos
Autores principales: O’Brien, Kevin T., Golla, Kalyan, Kranjc, Tilen, O’Donovan, Darragh, Allen, Seamus, Maguire, Patricia, Simpson, Jeremy C., O’Connell, David, Moran, Niamh, Shields, Denis C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349357/
https://www.ncbi.nlm.nih.gov/pubmed/30689642
http://dx.doi.org/10.1371/journal.pone.0210337