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Computational and experimental analysis of bioactive peptide linear motifs in the integrin adhesome
Therapeutic modulation of protein interactions is challenging, but short linear motifs (SLiMs) represent potential targets. Focal adhesions play a central role in adhesion by linking cells to the extracellular matrix. Integrins are central to this process, and many other intracellular proteins are c...
Autores principales: | O’Brien, Kevin T., Golla, Kalyan, Kranjc, Tilen, O’Donovan, Darragh, Allen, Seamus, Maguire, Patricia, Simpson, Jeremy C., O’Connell, David, Moran, Niamh, Shields, Denis C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349357/ https://www.ncbi.nlm.nih.gov/pubmed/30689642 http://dx.doi.org/10.1371/journal.pone.0210337 |
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