FGF21 trafficking in intact human cells revealed by cryo-electron tomography with gold nanoparticles

The fibroblast growth factor FGF21 was labeled with molecularly defined gold nanoparticles (AuNPs), applied to human adipocytes, and imaged by cryo-electron tomography (cryo-ET). Most AuNPs were in pairs about 80 Å apart, on the outer cell surface. Pairs of AuNPs were also abundant inside the cells...

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Detalles Bibliográficos
Autores principales: Azubel, Maia, Carter, Stephen D, Weiszmann, Jennifer, Zhang, Jun, Jensen, Grant J, Li, Yang, Kornberg, Roger D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349402/
https://www.ncbi.nlm.nih.gov/pubmed/30688648
http://dx.doi.org/10.7554/eLife.43146

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349402/
https://www.ncbi.nlm.nih.gov/pubmed/30688648
http://dx.doi.org/10.7554/eLife.43146

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