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Integrin alpha11 is an Osteolectin receptor and is required for the maintenance of adult skeletal bone mass

We previously discovered a new osteogenic growth factor that is required to maintain adult skeletal bone mass, Osteolectin/Clec11a. Osteolectin acts on Leptin Receptor(+) (LepR(+)) skeletal stem cells and other osteogenic progenitors in bone marrow to promote their differentiation into osteoblasts....

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Detalles Bibliográficos
Autores principales: Shen, Bo, Vardy, Kristy, Hughes, Payton, Tasdogan, Alpaslan, Zhao, Zhiyu, Yue, Rui, Crane, Genevieve M, Morrison, Sean J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349404/
https://www.ncbi.nlm.nih.gov/pubmed/30632962
http://dx.doi.org/10.7554/eLife.42274