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Integrin alpha11 is an Osteolectin receptor and is required for the maintenance of adult skeletal bone mass
We previously discovered a new osteogenic growth factor that is required to maintain adult skeletal bone mass, Osteolectin/Clec11a. Osteolectin acts on Leptin Receptor(+) (LepR(+)) skeletal stem cells and other osteogenic progenitors in bone marrow to promote their differentiation into osteoblasts....
Autores principales: | Shen, Bo, Vardy, Kristy, Hughes, Payton, Tasdogan, Alpaslan, Zhao, Zhiyu, Yue, Rui, Crane, Genevieve M, Morrison, Sean J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349404/ https://www.ncbi.nlm.nih.gov/pubmed/30632962 http://dx.doi.org/10.7554/eLife.42274 |
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