Design, synthesis, and biologic evaluation of novel chrysin derivatives as cytotoxic agents and caspase-3/7 activators

BACKGROUND: Chrysin (5,7-dihydroxyflavone) is a widely distributed natural flavonoid found in many plant extracts, honey and propolis. Several studies revealed that chrysin possesses multiple biological activities including anti-cancer effects. It has been established that activation of apoptosis is...

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Detalles Bibliográficos
Autores principales: Al-Oudat, Buthina Abdallah, Alqudah, Mohammad Ali, Audat, Suaad Abdallah, Al-Balas, Qosay Ali, El-Elimat, Tamam, Hassan, Mohammad Abdelhafeez, Frhat, Islam Nawaf, Azaizeh, Marwah Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349410/
https://www.ncbi.nlm.nih.gov/pubmed/30774307
http://dx.doi.org/10.2147/DDDT.S189476

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349410/
https://www.ncbi.nlm.nih.gov/pubmed/30774307
http://dx.doi.org/10.2147/DDDT.S189476

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