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ATF4 contributes to autophagy and survival in sunitinib treated brain tumor initiating cells (BTICs)

Receptor tyrosine kinase (RTK) pathways are known to play an important role in tumor cell proliferation of glioblastoma (GBM). Cellular determinants of RTK-inhibitor sensitivity are important to optimize and tailor treatment strategies. The stress response gene activating transcription factor 4 (ATF...

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Detalles Bibliográficos
Autores principales: Moeckel, Sylvia, LaFrance, Kelly, Wetsch, Julia, Seliger, Corinna, Riemenschneider, Markus J., Proescholdt, Martin, Hau, Peter, Vollmann-Zwerenz, Arabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349458/
https://www.ncbi.nlm.nih.gov/pubmed/30719230
http://dx.doi.org/10.18632/oncotarget.26569