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The Molecular Mechanism of Transport by the Mitochondrial ADP/ATP Carrier

Mitochondrial ADP/ATP carriers transport ADP into the mitochondrial matrix for ATP synthesis, and ATP out to fuel the cell, by cycling between cytoplasmic-open and matrix-open states. The structure of the cytoplasmic-open state is known, but it has proved difficult to understand the transport mechan...

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Detalles Bibliográficos
Autores principales: Ruprecht, Jonathan J., King, Martin S., Zögg, Thomas, Aleksandrova, Antoniya A., Pardon, Els, Crichton, Paul G., Steyaert, Jan, Kunji, Edmund R.S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349463/
https://www.ncbi.nlm.nih.gov/pubmed/30611538
http://dx.doi.org/10.1016/j.cell.2018.11.025