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Effects of BIS-MEP on Reversing Amyloid Plaque Deposition and Spatial Learning and Memory Impairments in a Mouse Model of β-Amyloid Peptide- and Ibotenic Acid-Induced Alzheimer’s Disease

Alzheimer’s disease (AD) is the main type of dementia and is characterized by progressive memory loss and a notable decrease in cholinergic neuron activity. As classic drugs currently used in the clinic, acetylcholinesterase inhibitors (AChEIs) restore acetylcholine levels and relieve the symptoms o...

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Detalles Bibliográficos
Autores principales: Wang, Yu, Xia, Jia, Shen, Mengjun, Zhou, Yifan, Wu, Zhe, Shi, Yuhuan, Xu, Jianrong, Hou, Lina, Zhang, Rui, Qiu, Zhuibai, Xie, Qiong, Chen, Hongzhuan, Zhang, Yongfang, Wang, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349730/
https://www.ncbi.nlm.nih.gov/pubmed/30723404
http://dx.doi.org/10.3389/fnagi.2019.00003