A Guide to PIN1 Function and Mutations Across Cancers

PIN1 is a member of a family of peptidylprolyl isomerases that bind phosphoproteins and catalyze the rapid cis–trans isomerization of proline peptidyl bonds, resulting in an alteration of protein structure, function, and stability. PIN1 is overexpressed in human cancers, suggesting it promotes tumor...

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Detalles Bibliográficos
Autores principales: El Boustani, Maguie, De Stefano, Lucia, Caligiuri, Isabella, Mouawad, Nayla, Granchi, Carlotta, Canzonieri, Vincenzo, Tuccinardi, Tiziano, Giordano, Antonio, Rizzolio, Flavio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349750/
https://www.ncbi.nlm.nih.gov/pubmed/30723410
http://dx.doi.org/10.3389/fphar.2018.01477

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349750/
https://www.ncbi.nlm.nih.gov/pubmed/30723410
http://dx.doi.org/10.3389/fphar.2018.01477

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