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Liver-Targeted Combination Therapy Basing on Glycyrrhizic Acid-Modified DSPE-PEG-PEI Nanoparticles for Co-delivery of Doxorubicin and Bcl-2 siRNA

Combination therapy based on nano-sized drug delivery system has been developed as a promising strategy by combining two or more anti-tumor mechanisms. Here, we prepared liver-targeted nanoparticles (GH-DPP) composed of 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-polyethylene glycol-polyetherimi...

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Detalles Bibliográficos
Autores principales: Tian, Guixiang, Pan, Ruiyan, Zhang, Bo, Qu, Meihua, Lian, Bo, Jiang, Hong, Gao, Zhiqin, Wu, Jingliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349772/
https://www.ncbi.nlm.nih.gov/pubmed/30723405
http://dx.doi.org/10.3389/fphar.2019.00004