The potential impact of hematocrit correction on evaluation of tacrolimus target exposure in pediatric kidney transplant patients

BACKGROUND: Tacrolimus is an important immunosuppressive agent with high intra- and inter-individual pharmacokinetic variability and a narrow therapeutic index. As tacrolimus extensively accumulates in erythrocytes, hematocrit is a key factor in the interpretation of tacrolimus whole blood concentra...

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Detalles Bibliográficos
Autores principales: Schijvens, Anne M., van Hesteren, Fransje H. S., Cornelissen, Elisabeth A. M., Bootsma-Robroeks, Charlotte M. H. H. T., Brüggemann, Roger J. M., Burger, David M., de Wildt, Saskia N., Schreuder, Michiel F., ter Heine, Rob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349786/
https://www.ncbi.nlm.nih.gov/pubmed/30374607
http://dx.doi.org/10.1007/s00467-018-4117-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349786/
https://www.ncbi.nlm.nih.gov/pubmed/30374607
http://dx.doi.org/10.1007/s00467-018-4117-x

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