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G418 induces programmed cell death in Acanthamoeba through the elevation of intracellular calcium and cytochrome c translocation

Acanthamoeba is a widely distributed opportunistic parasite which causes a vision-threatening keratitis and a life-threatening encephalitis. The cyst stage of this amoeba is especially resistant to currently used therapeutics and so alternative agents are urgently required. Growing evidence supports...

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Detalles Bibliográficos
Autores principales: Koutsogiannis, Zisis, MacLeod, Ewan T., Maciver, Sutherland K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349814/
https://www.ncbi.nlm.nih.gov/pubmed/30617503
http://dx.doi.org/10.1007/s00436-018-6192-0