sPIF promotes myoblast differentiation and utrophin expression while inhibiting fibrosis in Duchenne muscular dystrophy via the H19/miR-675/let-7 and miR-21 pathways

Duchenne muscular dystrophy (DMD) is a progressive, lethal, X-linked disease of skeletal and cardiac muscles caused by mutations in the dystrophin gene. Loss of dystrophin leads to muscle fiber damage and impairment of satellite cell asymmetric division, which are essential for muscle regeneration....

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Detalles Bibliográficos
Autores principales: Morgoulis, Daria, Berenstein, Peter, Cazacu, Simona, Kazimirsky, Gila, Dori, Amir, Barnea, Eytan R., Brodie, Chaya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349844/
https://www.ncbi.nlm.nih.gov/pubmed/30692507
http://dx.doi.org/10.1038/s41419-019-1307-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349844/
https://www.ncbi.nlm.nih.gov/pubmed/30692507
http://dx.doi.org/10.1038/s41419-019-1307-9

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